Mahmood Mirhoseini, M.D., D.Sc.
Principal Investigator
St. Luke's Medical Center
Milwaukee, Wisconsin

Exploration of methods to alleviate the effects of coronary artery disease has been a challenge to scientists. Efforts aimed at prevention include strategies to increase awareness and recommendations for lifestyle changes. Dietary modifications, smoking cessation programs and exercise regimes contribute to reducing the chances of developing severe coronary artery disease. In spite of these efforts, even among those who embrace heart healthy lifestyles, there are individuals who may still develop ischemic heart disease.

Coronary artery disease, once developed, can be moderated but cannot be reversed. Treatment options are determined by the stage and severity of disease. Medications, administered under close medical supervision, are sometimes helpful for mild to moderate disease. Therapeutic intervention is often required for more severe forms of disease. Treatment methods include coronary artery bypass surgery or balloon angioplasty.

An alternative treatment for those who do not respond to currently available forms of treatment may be a new procedure developed by Dr. Mirhoseini and investigated extensively at this


and other institutions around the world. This new method of treating coronary artery disease is revascularization of the ischemic myocardium by high power carbon dioxide laser, or Transmyocardial Laser Revascularization. The laser is used to create channels through the left ventricular cavity of the heart. These channels act as conduits to bring the blood supply of the ventricular cavity to the oxygen-starved heart muscle.

TMLR FAQ   ·   Additional Information & Facts

Further information is available upon request. A list of publications and/or reprints is available for your personal physician if he/she would like to request them.

For further information regarding Transmyocardinal Laser Revascularization, please contact:

Mahmood Mirhoseini, M.D., D.Sc

Research studies are supported in part by a grant from St. Luke's Foundation.